Stroke Research

Our stroke research is shared by a team of scientists, physicians, and other clinicians, who work together to better understand the causes of strokes and find new ways to improve treatment and perhaps, one day, discover methods to prevent a stroke from ever occurring. Below are highlights of our more recent stroke research.

Doctors Launch New Effort to Treat Stroke More Effectively

Just a small fraction of patients who have a stroke receive the only drug—tPA—available to treat the condition. Now doctors and scientists at the University of Rochester Medical Center have developed a potential new treatment that will reach a milestone in the next few months, when the experimental treatment is tested for the first time in people who have suffered a stroke, or “brain attack.” Read more...

Scientists Pinpoint Flaw, Offer New Promise for Stroke Treatment

The best treatment doctors currently have for stroke can accelerate the death of brain cells in addition to dissolving blood clots, researchers report in the journal Nature Medicine. But they also found good news: Another drug currently used to treat patients with severe sepsis counters the harmful effects, offering the possibility that a combination of two already-approved drugs might offer a powerful new stroke treatment that would give doctors a bigger window of time to treat patients. Read more...

Aspirin Works Better for Certain Stroke Patients

Certain patients at risk of developing a stroke are better off on aspirin than a popular blood thinner. Read more...

Alzheimer’s, Stroke Researcher Receives 10-Year MERIT Award

A researcher exploring ways to keep our brains healthy against the ravages of stroke and Alzheimer’s has been awarded a rare 10-year MERIT award from the National Institute on Aging. Read more...

Preventing Stroke Damage by Curbing Cells’ Auto-Destruct Signals

A compound already used to treat severe sepsis could open up a whole new approach for treating stroke, the leading cause of long-term disability in the nation. The research, reported in the March issue of Nature Medicine, shows that a compound known as activated protein C, or APC, directly protects brain cells that normally die as a result of a stroke by curbing the cells’ auto-destruct program. Read more...