Email this pageNephrology Research
Because we are constantly working to improve the quality of life of our patients, research is a central part of the activities within the Division of Pediatric Nephrology.
Laboratory research is broad-based within the field and includes:
- Physiological, cell biological, and molecular investigations into the understanding of how the kidney senses and responds to acid-base disorders.
- Investigations into how carbonic anhydrase, hensin, galectin - 3 and cyclophilins influence the kidney's response to acid-base disorders.
- The role of extracellular matrix proteins regulating acid-base transport was developed at the University of Rochester Medical Center.
Clinical research efforts include:
- Central Biochemistry Laboratory for the NIH Funded Chronic Kidney Disease in Children Study ( CKID) - 38 sites within the United States and Canada participate in the study involving over 500 children. The goal is to monitor the progression of kidney decease and it's effect on children.
- Mechanisms and pathogenesis of pediatric hypertension
- Investigation of kidney tubular disorders
- Mechanisms of pediatric nephrolithiasis (kidney stones)
- Use of iohexol to measure glomerular filtration rate in kidney patients
- Successful development of the Schwartz Formula, a formula used internationally in estimations of glomerular filtration rate
Nephrology