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Ping Tang, M.D., Ph.D.

Assistant Professor of Pathology and Laboratory Medicine

Surgical pathology; Breast, GU, and GI pathology
Cancer molecular biology, Early breast carcinogenesis

URMC Labs
601 Elmwood Ave., Rm G5264J
Rochester, NY 14642-8
Tel: (585) 275-6640
Fax: (585) 273-3637

Ping_Tang@urmc.rochester.edu

Dr. Tang recently received an Empire Clinical Research Investigator Program (ECRIP) award to fund the investigation of molecular markers that may predict a subgroup of ductal carcinoma in situ (DCIS) with high risk of progression to invasive ductal carcinoma (IDC). DCIS is a heterogeneous group of lesions that accounts over 20% of breast carcinoma diagnosed annually which has a 14-53% chance of progression to IDC over a 10-year period.

Qualifications

M.D., West China University of Medical Sciences, Chengdu, Sichuan 1983
Ph.D., Cancer Biology, University of Texas MD Anderson Cancer Center 1995
Postdoctoral Fellow, Neuro-Oncology, University of Texas MD Anderson Cancer Center 1995-1998
Resident in Pathology (AP/CP), North Shore University Hospital, Manhasset NY 1998-2002

Research Overview

Dr. Tang's Ph.D. research involved tumor necrosis factor signal transduction and protein processing at the University of Texas MD Anderson Cancer Center. From 1995-98 she served as a postdoctoral fellow there, studying growth inhibition of glioma cells by antisense TGF-alpha. Since her residency at North Shore and her surgical pathology fellowship at Yale, she has focused her research interest on early breast carcinogenesis.

Publications

Wei B, Wang J, Bourne P, Yang Q, Bu H, Tang P. Bone metastasis is strongly associated estrogen receptor-positive/progesterone receptor-negative breast carcinomas. Hum Pathol. 2008 Aug 18. [Epub ahead of print]

Tang P, Wei B, Hicks D, Skinner K, Bu H. Molecular classification of breast carcinoma and clinical application. J Chin Pathol, 2008, in press.

Tang P, Wei B, Bu H. Recent advances in ductal carcinoma in situ. Chinese J Clin Exp Pathol. 2008; 24:12-16.

Tang P, Wang J, Bourne P. Molecular classifications of breast carcinoma with similar terminology and different definitions: are they the same? Hum Pathol. 2008 Apr;39(4):506-13.

Hanley K, Wang J, Bourne P, Yang Q, Tang P. Lack of expression of androgen receptor may play a critical role in transformation from in situ to invasive basal subtype of high-grade ductal carcinoma of the breast. Hum Pathol. 2008 Mar;39(3):386-92.

Steinman S, Bourne P, Yang Q, Tang P, Wang J. Some DCIS is different molecularly from DCIS with co-existing IDC. Breast J. 2008 Jan-Feb;14(1):122-3.

Khilko N, Bourne P, Yang Q, Tang P. Mismatch repair genes hMLH1 and hMSH2 may not play an essential role in breast carcinogenesis. Int J Surg Pathol. 2007 Jul;15(3):233-41.

Steinman S, Wang J, Bourne P, Yang Q. Tang P. Expression of cytokeratin markers, ER-alpha, PR, HER-2/neu, and EGFR in pure ductal carcinoma in situ (DCIS) and DCIS with co-existing invasive ductal carcinoma (IDC) of the breast. Ann Clin Lab Sci. 2007 Spring;37(2):127-34.

Tang P, Hajdu SI, Lyman GH. Ductal carcinoma in situ: A review of recent advances. Curr Opin Obstet Gynecol. 2007 Feb; 19(1):63-67.

Tang P, Wang X, Schiffhauer L, Bourne P, Yang Q, Quinn A, Hajdu S. Expression patterns of ER-alpha, PR, HER-2/neu, and EGFR in different cell origin subtypes of high grade and non-high grade ductal carcinoma in situ. Ann Clin Lab Sci. 2006 Spring;36(2):137-43

Tang P, Wang X, Schiffhauer L, Bourne P, Yang W, Quinn A, Hajdu SI. Relationship between nuclear grade of ductal carcinoma in situ and cell origin markers. Ann Clin Lab Sci. 2006 Winter;36(1):16-22.

Tang P, Hajdu SI, Conte CC, Filardi DA. Incidental finding of mammary carcinoma in lumpectomy specimens. Ann Clin Lab Sci. 2003 Winter;33(1):23-31.

Tang P, Teichberg S, Roberts B, Hajdu SI. Ultrastructure of the periductal area of comedo carcinoma in situ of the breast. Ann Clin Lab Sci. 2001 Jul;31(3):284-90.

Tang P, Mckinley MJ, Sporrer M, Kahn E. Inlet Patch: Prevalence, Histologic type, and its associated lesion. 2004. Arch Pathol Lab Med, 128: 444-447.

Tang P, Ackerman AB. Benign Metastasis. http://www.derm101.com April-June 2004, volume 10, #2.

Elefteriades J, Lovoulos C, Edwards R, Tittle S, Riley T, Tang P, Rocco E, and Kopf G. Novel Technique for isolated accessory right heart transplantation for congential heart disease. J Thorac Cardiovasc Surg, 2003, 125: 1283-1290.

Tang P, Jasser SA, Sung JC, Shi Y, Steck PA, Yung WK. Transforming growth factor-alpha antisense vectors can inhibit glioma cell growth . J Neurooncol. 1999 Jun;43(2):127-35.

Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA. Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res. 1998 Dec 1;58(23):5285-90. Erratum in: Cancer Res 1999 Mar 1;59(5):1167.

Tang P, Steck PA, Yung WK. The autocrine loop of TGF-alpha/EGFR and brain tumors. J Neurooncol. 1997 Dec;35(3):303-14. Review.