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Linda Schiffhauer, M.D.

Assistant Professor of Pathology and Laboratory Medicine

Surgical Pathology, Breast Pathology
Protein Expression in Breast Cancer

URMC Labs
601 Elmwood Ave., Rm G-5257
Rochester, NY 14642-8626
Tel: (585) 275-3270
Fax: (585) 273-3637

Linda_Schiffhauer@urmc.rochester.edu

Dr. Schiffhauer's clinical interests include general surgical pathology and breast pathology. She has collaborated with researchers in Medicine and Radiology in investigating the accuracy and efficiency of different methods for the diagnosis and treatment of breast cancer. She recently received a Dean's Teaching Fellowship award to compare the use of virtual microscopy versus light microscopy in the teaching laboratory setting.

Qualifications

M.D., Albany Medical College 1992
Resident in Anatomic Pathology, University of Pennsylvania 1992-96
Fellow, Surgical Pathology and Research, University of Pennsylvania 1996-97
National Research Service Award, Breast Cancer Research 1996-97

Research Overview

Dr. Schiffhauer's research activities have focused on the expression of C35 and HER-2 in breast cancer.

Publications

Schiffhauer LM, Griggs JJ, Ahrendt GM, Sorbero ME, "Docetaxel and Trastuzumab as Primary Systemic Therapy for HER-2/neu Overexpressing Breast Cancer". Abstract, ASCO Program/Proceedings book, Annual Meeting of the American Society of Clinical Oncology, Chicago, IL, May 2003.

Ning R, Conover D, Yu Y, Schiffhauer L, Lu X, Cullinan J, Ahrendt G, Robinson A, Willson K. Hot topic: flat panel detector-based cone beam volume CT breast imaging: Specimen study. Radiological Society of North America 88th Annual Meeting, Chicago, IL, December 2002.

Ning R, Conover D, Chen B, McHugh L, Cullinan J, Yu R. Flat panel detector-based cone beam volume CT breast imaging: phantom and specimen study. Proc. SPIE 4682:218-227, 2002.

Depowski P, Mulford D, Minot D, Bourne P, McCabe C, McHugh L. Comparative Analysis of Her-2/neu Protein Overexpression in Breast Cancer Using Paraffin-Embedded Tissue and Cytologic Specimens. Abstract. United States and Canadian Academy of Pathology 91st Annual Meeting, Chicago, IL, March 2002. Modern Pathology. 15(1): 70A, 2002.

Ning R, Chen B, Conover D, McHugh L, Cullinan J., Yu R. Flat panel detector-based cone beam volume CT mammography imaging: preliminary phantom study. Proc. SPIE 4320:601-610, 2001.

Chan E, Thakur A, Farid L, Lessin S, Uberti-Benz M, James W. . Pemphigus vulgaris of the cervix and upper vaginal vault: a cause of atypical papanicolaou smears Arch Dermatol. 1998 Nov;134(11):1485-6.

Lakhani SR, Jacquemier J, Sloane JP, Gusterson BA, Anderson TJ, van de Vijver MJ, Farid LM, Venter D, Antoniou A, Storfer-Isser A, Smyth E, Steel CM, Haites N, Scott RJ, Goldgar D, Neuhausen S, Daly PA, Ormiston W, McManus R, Scherneck S, Ponder BA, Ford D, Peto J, Stoppa-Lyonnet D, Easton DF, et al. Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. J Natl Cancer Inst. 1998 Aug 5;90(15):1138-45.

Thakur S, Zhang HB, Peng Y, Le H, Carroll B, Ward T, Yao J, Farid LM, Couch FJ, Wilson RB, Weber BL. Localization of BRCA1 and a splice variant identifies the nuclear localization signal. Mol Cell Biol. 1997 Jan;17(1):444-52.

Couch FJ, Farid LM, DeShano ML, Tavtigian SV, Calzone K, Campeau L, Peng Y, Bogden B, Chen Q, Neuhausen S, Shattuck-Eidens D, Godwin AK, Daly M, Radford DM, Sedlacek S, Rommens J, Simard J, Garber J, Merajver S, Weber BL. BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nat Genet. 1996 May;13(1):123-5.

Couch FJ, Farid LM, Weber BL. Genetic analysis of susceptibility to inherited breast cancer with emphasis on BRCA1 and BRCA2. In Weinstein RS, Advances in Pathology and Laboratory Medicine, Volume 9, St. Louis, Mo: Mosby-Year Book, p361-391, 1996.