Saturday, Sunday, Monday, Tuesday
Sunday July 15th, 2007
NCL Congress
8:30AM- 12:30PM
Welcoming remarks: David Pearce, University of Rochester Medical Center
Session II: Infantile NCL and CLN1
Chair: Beverly Davidson
Plenary Lecture
Maiken Nedergaard, University of Rochester Medical Center, USA -
Astrocytes as active participants in brain function
NCL Plenary Lecture
Sandra Hoffman, University of Texas Southwestern, USA
Palmitoyl-Protein Thioesterase and the Molecular Basis of Infantile NCL
Invited Speakers
Anu Jalanko, National Public Health Institute, Finland
Mouse Ppt1 deficiency is linked to defects in fundamental cellular processes
Mark Sands, Washington University School of Medicine, USA - Systemic and metabolic abnormalities associated with murine Infantile Neuronal Ceroid Lipofuscinosis
Break
NCL presentations chosen from submitted abstracts.
Annina Lyly, National Public Health Institute, Finland - Novel interacting partner of palmitoyl protein thioesterase 1 links PPT1 to lipid metabolism
Catherine Kielar, Institute of Psychiatry, King’s College London, United Kingdom - Pathological involvement of the thalamus in mouse models of NCL extends to non-sensory relay nuclei
Chris Korey, College of Charleston, USA - Genetic and Cell Biological Approaches to Characterizing Ppt1 Function in Drosophila
Poster Session I
Lunch
Sunday July 15th, 2007
NCL Congress
1:30PM- 5PM
Session III: Late-Infantile NCL and CLN2
Chair: Jonathan Cooper
Plenary Lecture
Michael Brenner, University of Alabama at Birmingham, USA
Alexander disease: a genetic disorder of astrocytes
NCL Plenary Lecture
David Sleat, Center for Advanced Biotechnology and Medicine, University of Medicine and Dentistry of New Jersey, USA
Lysosomal proteomics and human disease.
Invited Speakers
David Sleat, Center for Advanced Biotechnology and Medicine, University of Medicine and Dentistry of New Jersey, USA
Rescuing the LINCL phenotype in CLN2 mutant mice
Adam Golabek, Institution for Basic Research, Staten Island, USA
The role of prosegment in TPP I activity and stability
Joan Coates, College of Veterinary Medicine, University of Missouri-Columbia, USA
Phenotypic characterization of a Dachshund model for CLN2
Poster Session II - Presenters will be with posters
Dinner
Workshop
Clinical Scientists – Organizer Jonathan Mink