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Ph.D. (1992)
Indiana University

Leif P. Olson, Ph.D.
Research Associate Professor of Anesthesiology

Primary Appointment:
Anesthesiology

 
 
Contact Information:
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 604
Rochester, New York 14642
Medical Center, Room 4-7568
Phone: (585) 275-2659
Fax: (585) 273-2652
Research Overview
Design and synthesis of mitochondrially targeted drugs and prodrugs, mechanisms of ROS interactions, interactions with drugs and biomolecules.

Recent Publications

Olson LP  (2000)  A DFT and PM3 study of a hypothetical silicon-based s-allyl cation and s-allyl radical and higher homologues.  Org. Lett. 2:3059.

Olson LP; Kuwata KT; Bartberger MD, and Houk KN  (2002)  Conformation-dependent state selectivity in O-O cleavage of ONOONO: An ‘Inorganic Cope Rearrangement’ helps explain the observed negative activation energy of nitrix oxide by dioxygen.  J. Am. Chem. Soc. 124:9469.

Olson LP, Bartberger MD, and Houk KN  (2003)  Peroxynitrate and peroxynitrite: A complete basis set investigation of similarities and differences between these NOx species.  (2003)  J. Am. Chem. Soc. 125:3999.

Zhao Y, Houk KN, and Olson LP  (2004)  Mechanisms of peroxynitrous acid and methyl peroxynitrite, ROONO (R = H, Me) rearrangements: A conformation-dependent hemolytic dissociation.  J. Phys. Chem. 108:5864.

Olson LP  (2004)  Computed structures and reaction enthalpies of the rearrangements of certain cyclic hexaalkynes to ortho-arene cyclynes.  THEOCHEM 680:65.

Bringley JF, Rajeswaran M, Olson LP, and Liebert NM  (2005)  Silver-halide/organic-composite structures: Toward materials with multiple photographic functionalities.  J. Solid State Chem. 178:3074.

Olson LP, Whitcomb DR, Rajeswaran M, Blanton TN, and Stwertka BJ  (2006)  The simple yet elusive crystal structure of silver acetate and the role of the Ag-Ag bond during the thermally induced reduction of silver carboxylates.  Chemistry of Materials (in press).

Norton JE, Olson LP, and Houk KN  (2006)  Theoretical studies of quantum amplified isomerization for imaging systems.  J. Am. Chem. Soc. (submitted).

 

PubMed Publication List

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and provides complete abstracts of all 'olson lp' publications,
as well as links to the full text of many articles (at journal homepages).



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