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Department of Dermatology

beck photo

 

Lisa A. Beck, M.D.

Department of Dermatology
Lisa_Beck@urmc.rochester.edu

_________________________________________________

Dr Lisa Beck brings more that 17 years' experience to the treatment of atopic deramtitis and eczema. She is currently involved in an NIH-funded study to determine why certain patients are susceptiable to the herpes simplex and staphylococcus aureus.

Education and Training

1977 - 1981 B.A. in Chemistry (Magna cum Laude, Phi Beta Kappa) Mt. Holyoke College, South Hadley, MA
1981 - 1985 M.D., SUNY Stony Brook Medical School, Stony Brook, NY
1985 - 1987 Internship and 2nd year of Residency, Internal Medicine Strong Memorial Hospital, Rochester, NY
1987 - 1990 Fellowship, Dermatology (Chief Resident in final year) Duke University Medical Center, Durham, NC
1992 - 1994 Fellowship, Immunology Research (Mentor: Robert Schleimer, Ph.D.) Johns Hopkins Division of Clinical Immunology

Academic Appointments and Professional Experience

1990 - 1992 Clinical Instructor of Dermatology
Johns Hopkins University, Director of Dermatology
Johns Hopkins Bayview Medical Center (Francis Scott Key Hospital)
1994 - 2002 Assistant Professor of Dermatology (Primary)
and Medicine, Division of Clinical Immunology (Secondary)
Johns Hopkins University
1998 - 2002 Director of Dermatology
Johns Hopkins Bayview Medical Center
2002 - 2006 Associate Professor of Dermatology (Primary)
and Medicine, Division of Clinical Immunology (Secondary)
Johns Hopkins University
12006-Present Associate Professor of Dermatology, University of Rochester, School of Medicine, Rochester, New York

Honors and Awards

1992 Teaching Appreciation Award, Johns Hopkins University, Dermatology Dept.1992 Internal Medicine Teaching Award, Francis Scott Key Medical Center
1994 Physician-Scientist Award, National Institutes of Health
1994 Dermatology Foundation Research Foundation
1996 Mentor for Howard Hughes Summer Fellowship Recipient
2005 Mentor for Fujisawa AAAAI Research Grant Recipient
2005 Mentor for NEASE Skin Research Grant Recipient

Professional Societies and Committee

1990 - present American Academy of Dermatology
1990 - present Woman's Dermatologic Society
1992 - present American Academy of Allergy, Asthma and Immunology
1994 - present Society of Investigative Dermatology
1994 - present Dermatology Foundation
1999 - present American Association of Immunologists
2001 Novartis Pharmaceuticals Corp., Mock Advisory Committee for ElidelTM
2001 - present Member of the AAAAI Interest Section Grant Review Committee.
2002 - present Scientific Advisor and Board Member for the National Eczema Association for Science and Education (NEASE).
2001 Member of the AAAAI Committee reviewing ERT grants
2002 Member and Speaker at Novartis Pharmaceuticals Corporation Advisory Board Program
2003 Chair of the AAAAI Committee reviewing Woman Physician in Allergy Award Grant Applicants.
2002 Member of NIH Advisory Group convened to discuss Smallpox Vaccination and risk to patients with Atopic Dermatitis.
2002 - present Ad Hoc Reviewer for the SID abstracts (in Auto-immunity and Inflammation)
2003NIH Ad Hoc Reviewer for NIAID Biodefense Grants (Priti Mehotra-SRA).
2003 Internal Advisor for NIH Program Project Grant entitled, "Peripheral Neural Mechanisms of Itch", P.I. Robert LaMotte, Ph.D.
2003 - present National Eczema Association for Science and Education Scientific Advisory Board
2004 NEASE Reviewer for ApotheCom website entitled, "EczemaNow Report"
2004 NIH Ad Hoc Reviewer for KO1 and K08 awards for AMS committee

Meeting Organization Activities

1997 Organizing Board for the 1st AAD/AAAAI NYC meeting.
2003 Organizing Board for the 3rd AAD/AAAAI NYC meeting
2005 Organizing Board for the 4th AAD/AAAAI NYC meeting
1996 - present AAAAI Dermatology Interest Section, Chair of Seminars and/or Symposia.
1998 - present AAAAI Dermatology Interest Section, Chair and Moderator of Course.
2003 Co-organizer of AAAAI Clinical Year-in-Review Lectures.
2003 Program Director for 13th Annual Johns Hopkins Asthma and Allergy Symposium, entitled "The Skin as an Immune Organ." (Picked speakers and topics and raised all the funds for this event.)

Journal Articles

  1. Beck LA, Herzberg AJ, White PF, Burton CS. Merkel Cell Tumor. Cutis, 1989; 44: 295-99.
  2. Stellato C, Beck LA, Gorgone GA, Proud D, Schall TJ, Ono SJ, Lichtenstein LM, Schleimer RP. Expression of the chemokine RANTES by a human bronchial epithelial cell line: Modulation by cytokines and glucocorticoids. J Immunol, 155:410-418, 1995.
  3. Beck L, Stellato C, Gorgone G, Schall TJ, Leopold D, Bickel C, Baroody F, Bochner B, Schleimer RP. Detection of the chemokine RANTES and Endothelial adhesion molecules in Nasal Polyps. J Allergy and Clin Immunol, 98:766-780, 1996.
  4. Schwiebert LA, Beck LA, Stellato C, Bickel CA, Bochner BS, Schleimer RP. Glucocorticosteroid inhibition of cytokine production: Relevance to antiallergic actions. J Allergy and Clin Immunol, 97:143-152, 1996.
  5. Morison WL, Marwaha S, Beck L. Oral PUVA-induced phototoxicity: Incidence and causes. J Am Acad Derm, 36: 183-185, 1997.
  6. Simons JW, Jaffee EM, Weber C, Levitsky HI, Nelson WG, Carducci MA, Lazenby AJ, Cohen L, Finn CC, Clift SM, Hauda KM, Beck LA, Leiferman KM, Owens AH, Piantadosi S, Dranoff, G Mulligan RC, Pardoll DM, Marshall FF. Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Research, 57:1537-1546, 1997.
  7. Beck L, Dalke S, Leiferman KM, Bickel C, Hamilton R, Rosen H, Bochner BS, Schleimer RP. Cutaneous Injection of RANTES causes eosinophil recruitment: Comparison of nonallergic and allergic human subjects. J Immunol, 159: 2962-2979, 1997.
  8. DeYampert NM, Beck LA. Eosinophilia and multiple erythematous indurated plaques. Arch Derm, 133: 1579-1584, 1997.
  9. Matsumoto K, Appiah-Pippim J, Schleimer RP, Bickel C, Beck L, Bochner BS. CD44 and CD69 are activation markers for human eosinophils. Am Rev Respir Cell Mol Biol, 18:860-866, 1998.
  10. Beck LA, Stellato C, Schleimer RP. Studies on the role of chemokines in allergic disease. In: Innovative Strategies for Immune Modulation of Host Reponses. Ed: M. Ballow. (Proc of the 1998 Natl. Immunology meeting, Bodega Bay, CA). Osprey Communications, Inc. 69-80, 1998.
  11. Kim YK, Uno M, Hamilos DL, Beck L, Bochner B, Schleimer R, Denburg JA. Immuno-localization of CD34 in nasal polyposis: Effect of topical corticosteroids. Am Rev Respir Cell Mol Biol, 20:388-397, 1999.
  12. Stellato C, Matsukura S, Fal A, White J, Beck LA, Proud D, Schleimer RP. Differential Regulation of Epithelial-derived C-C Chemokine Expression by IL-4 and the Glucocorticoid Budesonide. J Immunol, 163:5624-5632, 1999.
  13. Nickel, R., Beck L.A., Stellato C., and Schleimer R.P. Chemokines and allergic disease. J Allergy Clin Immunol , 104:723-742, 1999.
  14. Chen R, Burke T, Cumberland J, Beck L, Casolaro V, Georas S. Glucocorticoids inhibit calcium- and calcineurin-dependent activation of the human IL-4 promoter. J Immunol, 164: 825-832, 2000.
  15. Cooper P, Beck LA, Espinel I, Deyampert NM, Hartnell A, Paredes W, Guderian RH, Nutman TB. Endothelial expression of RANTES and eotaxin-1 is associated with eosinophil infiltration into the skin after the treatment of onchocerchiasis with ivermectin. Clin Immunol, 95:51-61, 2000.
  16. Lee SC, Brummet ME, Shahabuddin S, Woodworth TG, Georas SN, Leiferman KM, Gilman SC, Stellato C, Gladue RP, Schleimer RP, Beck LA. Cutaneous Injection of Human Subjects with Macrophage Inflammatory Protein-1alpha Induces Significant Recruitment of Leukocytes. J Immunol, 164: 3392-3401, 2000.
  17. Beck LA, Leung DYM. Allergen sensitization through the skin induces systemic allergic responses. J Allergy Clin Immunol, 106:S258-63, 2000.
  18. Stellato C, Beck LA. Expression of eosinophil-specific chemokines by human epithelial cells. Chem Immunol. 2000;76:156-76.
  19. Seminario M-Ca, Guo J, Bochner BS, Beck LA, Georas SN. Human eosinophils constitutively express NFATp and NFATc. J Allergy Clin Immunol, 107(1):143-152, 2001.
  20. Stellato C, Brummet ME, Plitt JR, Ponath PD, Baroody F, Liu MC, Beck LA. Cutting Edge: Expression of the CC chemokine receptor CCR3 in human airway epithelial cells. J Immunol, 166:1457-1461, 2001.
  21. Georas SN, Beck LA, Stellato CS. What is eotaxin doing in the pleura? Insights into innate immunity from pleural mesothelial cells. Am J Respir Cell Mol Biol, 26:384-387, 2002.
  22. Eichenfield LF, Hanifin JM, Beck LA, Lemanske RF, Sampson HA, Weiss ST, Leung DYM. Atopic Dermatitis and Asthma: Parallels in the Evolution of Treatment. Pediatrics, 2003; 111, 608-616.
  23. Eichenfield LF, Beck LA. Elidel¨ (Pimecrolimus) Cream 1%: A Nonsteroid Topical Agent for the Treatment of Atopic Dermatitis. J Allergy Clin Immunol. 2003 May;111(5):1153-68.
  24. Garrett J, Jameson S, Thompson, B, Collins M, Wagoner LE. Freese DK. Beck LA, Boyce JA, Filopovich E, Villanueva J. AssaĠad A, Rothenberg M. Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes. J Allergy Clin Immunol. 2004 Jan;113(1):115-9.
  25. Esche C, De Benedetto A, Beck, LA. Keratinocytes in atopic dermatitis: inflammatory signals. Curr Allergy Asthma Rep. 2004 Jul;4(4):276-84.
  26. Sha Q, Truong-Tran, AQ, Plitt JR, Beck LA, Schleimer RP. Activation of Airway Epithelial Cells by Toll-like Receptor Agonists. Am J Respir Cell Mol Biol, 2004 31:358-364.
  27. Beck LA, Marcotte GV, MacGlashan D, Togias A, Saini S. Omalizumab induced reductions in mast cell FceR1 expression and function. J Allergy Clin Immunol. 2004 Sep;114(3):527-3.
  28. Paltiel M, Zeichner J, Beck LA. The Differential Diagnosis of Atopic Dermatitis (CME). J. Am. Acad. Derm. Submitted (in revision), 2005.
  29. Esche C, Stellato C, Beck LA. Chemokines: Key players in both innate and adaptive immunity. J. Invest. Derm. (Invited, Peer-Reviewed) 2005 125:615-628.
  30. Beck LA. The efficacy and safety of Tacrolimus ointment: Clinical review. (supplement) J. Am Acad Derm 2005; 53(2 Suppl 2):S165-70.
  31. Abdelilah SG, Wellemans V, Bellesort F, Hamid Q, Beck LA, Lamkhioued B. Increased expression of Th2 associated chemokines (eotaxin and MCP-4) in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. J. Invest. Derm. submitted, 2005.
  32. Barnes, KC, Grant A, Baltadjieva D, Berg T, Zhang S, Zambelli-Weiner A, Ehrlich E, Zardkoohi O, BrummetME, Stockton M, Beaty TH, Beck LA, Becker KG, Garcia JGN, Mathias RA. Synergistic effect between the CD14 (-260) polymorphism and markers in a novel candidate gene acyloxyacyl hydroxylase (AOAH) among asthmatics. J Allergy Clin Immunol. Submitted (in revision), 2005.
  33. L. A. Beck, B. Tancowny, M. E. Brummet, S. Y. Asaki, S. L. Curry, M. B. Penno, C. E. Austin, A. Bahl, C. Stellato. Functional Analysis of the Chemokine Receptor CCR3 on Airway Epithelial Cells. To be submitted to J Allergy Clin Immunol. (under review by Astra-Zeneca), 2005.
  34. Beck LA, Stellato C, Shahabuddin S, Brummet M, Tancowny B, Plitt J, Barnette MS, Brawner M, Schleimer RP. Expression of Chemokine Receptors on Human Airway Epithelial Cells and the Role of CCR5 in Wound Repair., To be submitted to Am J Respir Cell Mol Biol,(manuscript in preparation), 2005.
  35. McGirt L, Gober L, Saini, S, Beck LA. Sulfasalazine is Beneficial in the Treatment of Chronic Idiopathic Urticaria. To be submitted to Arch. Derm. ,(manuscript in preparation), 2005.
  36. Tzu J, Beck LA. Chronic Urticaria Associated in a Patient with Polyglandular Autoimmune Syndrome Type III. submitted to J. Amer. Acad. Dermatol., 2005.

Book Chapters:

  1. Morison W, Beck LA. Chapter: Psoriasis. Stein J.H. editor, in Textbook of Internal Medicine, Mosby. St Louis, Missouri, 1994.
  2. Simmons-O'Brien E, Beck LA. Chapter: Dermatological Manifestations of Gastrointestinal Diseases. Stein J.H. editor, in Textbook of Internal Medicine, Mosby. St Louis, Missouri, 1994.
  3. Beck LA, Charlesworth EN. The skin as an immune organ. E.N. Charlesworth, editor, in Cutaneous Allergy for the Clinician. Blackwell Science, Inc., Massachusetts, 1-34, 1996.
  4. Beck L, Georas SN. Expression of cell adhesion molecules in eosinophilic disorders of the skin and nose. B.S. Bochner, editor, in Adhesion Molecules in Allergic Disease. Marcel Dekker, Inc., New York, 339-67, 1997.
  5. Beck L. The role of food additives in urticaria. M.V. Dahl, editor, in Current Opinion in Dermatology. Rapid Science Publishers, Philadelphia, PA. 3-8, 1997.
  6. Schleimer RP, Beck L, Schwiebert L, Stellato C, Bochner BS. Inhibition of inflammatory cell recruitment by glucocorticoids: cytokines as primary targets. Schleimer RP, Busse WW, O'Byrne P. editors, in Topical glucocorticoids in asthma: mechanisms and clinical actions. New York: Marcel Dekker, Inc., 1997; 203-238.
  7. Stellato C., Beck L.A. Expression of eosinophil-specific chemokines by human epithelial cells. G. Marone editor, in Human Eosinophils: Biological and Clinical Aspects. Basel, Karger, Vol. 76, 156-176, 2000.
  8. Beck LA, Provost TP. Urticaria. T Provost, G Anhalt, J Flynn, editors in Cutaneous Medicine: Cutaneous Manifestations of Systemic Disease, B. C. Decker, Inc., Hamilton, Ontario, 250-262, 1999.
  9. Beck LA, Provost TP. Mastocytosis. T Provost, G Anhalt, J Flynn, editors in Cutaneous Medicine: Cutaneous Manifestations of Systemic Disease, B. C. Decker, Inc., Hamilton, Ontario, 681-688, 1999.
  10. Beck LA, Stellato C, Shahabuddin S, Nickel R, Schleimer RP. The role of chemokines in allergic diseases of the airways. Letts LG, Morgan DW., editors in Inflammatory Processes: Molecular Mechanisms and Therapeutic Opportunities. Basel: Birkhauser Verlag publisher, 2000.
  11. Bochner BS, Beck LA. Adhesion Molecules and Their Role in Allergic Skin Diseases. Leung DYM and Greaves M., editors in Allergic Skin Diseases: Causes and Treatment. St Louis: Mosby Yearbook, Inc., 2000; 87-112.
  12. Beck LA. Atopic Dermatitis. Lichtenstein LM, Busse WW and Geha RS., editors in Current Therapy in Allergy, Immunology and Rheumatology. St Louis: Mosby Yearbook, Inc., 2004.
  13. Rencic A, Beck LA. Regulation of the Production and Activation of Eosinophils, Freedberg I, Eisen A, Wolff K, Austen KF, Goldsmith L, and Katz SI, , editors in Dermatology in General Medicine. NY: McGraw-Hill Co., 2004.

Other Professional Acomplishments

Spring 1997 Interviewed regarding allergic skin diseases for the Today Show entitled "Allergy Relief Series".
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