Aab Institute for Biomedical Sciences

Center for Vaccine Biology and Immunology

Tim Mosmann Ph.D. Director, Center for Vaccine Biology and Immunology Professor of Microbiology and Immunology Tim_Mosmann@urmc.rochester.edu

Building on the existing strong programs in Immunology, Microbiology and Vaccine Biology at the University of Rochester, the Center for Vaccine Biology and Immunology focusses on basic research into immunological mechanisms, and also on the long-term goal of helping to design the next generation of vaccines.

The Center occupies 31,500 square feet of exceptional research space on the top floor of the recently (1999) constructed Kornberg Medical Research Building at the University of Rochester Medical Center. In addition, faculty throughout the Medical Center, including those in the new research building, share state-of-the-art core facilities which are housed in the new research building and elsewhere.

• Department of Microbiology and Immunology
• Allergy, Rheumatology and Immunology Unit
• Infectious Diseases Unit
• Cancer Center
• Clinical Trials Database
• HIV Vaccine Trials Unit

The University of Rochester's Department of Microbiology and Immunology has been awarded several highly competitive training grants from the National Institutes of Health (NIH). These training grants provide for specific educational and training opportunities, as well as stipend support, for Microbiology and Immunology Ph.D. students working in the areas of Immunology, Microbial Pathogenesis, Oral Microbiology, and HIV Pathogenesis. Additional information is available at:

Training Grants

Post-doctoral positions:

Post-doctoral positions with members of the Center are available. Applications should be sent to the investigator.

Current Faculty of the Center for Vaccine Biology and Immunology:

Tim R. Mosmann, Ph.D.
Director and Professor of Microbiology and Immunology.
Research interests: The regulation of cytokine responses of human and mouse T-cell subsets in infections asthma, allergy and autoimmunity.

Nick Crispe, Ph.D.
Associate Director of the Center for Vaccine Biology and Immunology; Professor of Microbiology and Immunology.
Research interests: Cell cycle control and apoptosis in T lymphocytes in vivo.

Deborah Fowell, Ph.D.
Assistant Professor of Microbiology and Immunology in the Center for Vaccine Biology and Immunology.
Research interests: Differentiation of CD4 T lymphocytes in infectious and autoimmune disease.

Alexandra Livingstone, Ph.D.
Research Associate Professor of Microbiology and Immunology in the Center for Vaccine Biology and Immunology.
Research interests: Understanding mechanisms for generating and maintaining T cell memory, with particular emphasis on responses primed by immunization with dendritic cells.

Jim Miller, Ph.D.
Professor of Microbiology and Immunology in the Center for Vaccine Biology and Immunology.
Research Interests: Molecular and cellular events that regulate T cell signaling and activation.

Andrea Sant, Ph.D.
Professor of Microbiology and Immunology in the Center for Vaccine Biology and Immunology.
Research Interests: MHC class II restricted antigen presentation.

David J. Topham, Ph.D.
Assistant Professor of Microbiology and Immunology in the Center for Vaccine Biology and Immunology.
Research interests: T cell immunity against respiratory viruses.

Kim, Minsoo, Ph.D.
Associate Professor of Microbiology and Immunology in the Center for Vaccine Biology and Immunology.
Research Interests: Dynamic regulation of leukocyte adhesion and migration.

Investigators in the center have extensive collaborations with investigators in various departments resulting in several large collaborative grants and contracts in the areas of influenza, human immunology, mathematical modeling of immune response and responses in immunocompromized populations, vaccine response evaluation, autoimmunity and HIV vaccines.

Other Links:

• Faculty Publications

• Faculty members in Graduate Education in Biomedical Sciences: Cluster for Immunology, Microbiology and Vaccine Biology

• Selected Courses in Microbiology and Immunology (and Related Disciplines)

• University of Rochester Medical Center

• Recent News at the URMC