Rochester Oral Biology Research Conference

June 26-28, 2008
Saliva and Salivary Gland Function

All seminars will take place in the Class of ’62 Auditorium of the Kornberg Medical Research Building, 601 Elmwood Ave.

Thursday June 26

1:00-2:30 Registration
2:30-2:45 Opening Remarks/Housekeeping
2:45-5:45 Session I: Salivary Gland Development and Maintenance
Co-Chairs: Catherine Ovitt & Kelly Ten Hagen
2:45-3:15 Monn Monn Myat (Cornell): Salivary gland morphogenesis in Drosophilia
3:15-3:45 Kelly Ten Hagen (NIDCR): The role of mucin-type protein    glycosylation during development
3:45-4:15 Mindy Larsen (SUNY-Albany): Cell-cell and cell-matrix interactions in salivary gland development
4:15-4:30 Break
4:40-5:10 Denise Faustman (Harvard Medical School): Reversal of Sjögren’s-like syndrome from NOD mice to humans?
5:10-5:40 Catherine Ovitt (Univ Rochester): Postnatal salivary gland progenitor cells
5:45-7:00 Dinner
7:15-8:00 Keynote Speaker - Lawrence A. Tabak Lectureship
Bruce Baum (NIDCR):  Gene therapy for radiation-induced salivary gland damage

 

Friday June 27

8:00-8:45 Breakfast
9:00 James Melvin (Univ Rochester): Recognition of Abstract Awards
9:00-12:00 Session II: Cell Signaling in Epithelial Cells
Co-Chairs: David Yule & Indu Ambudkar
9:00-9:30 James Sneyd (Auckland): Part I -  A systems biology approach to signaling
9:30-10:00 David Yule (Univ Rochester): IP3-Ca2+ signaling
10:00-10:30 Trevor Shuttleworth (Univ Rochester): Ca2+ entry pathways
10:30-10:45 Break
10:55-11:25 Stephen Soltoff (Beth Israel Deaconess Medical Center): Salivary gland signaling cascades
11:25-11:55 Indu Ambudkar (NIDCR):  Function of TRP channels in Ca2+ entry
12:00-1:00 Lunch
1:00-2:30  Poster Session: Co-chairs and Poster-Abstract Judges:Maria Kukuruzinska (Boston Univ), Mira Edgerton (SUNY Buffalo), Anil Menon (Univ of Cincinnati)
2:45-5:45 Session III: The Epithelial Fluid Secretion Mechanism
Co-Chairs: Ted Begenisich & Shmuel Muallem
2:45-3:15 Edmund Crampin (Auckland): Part II - A systems biology approach to secretion
3:15-3:45 James Melvin (Univ Rochester): Cl channels and fluid secretion
3:45-4:15 Ted Begenisich (Univ Rochester):  K channel function / interaction of Slo and IK1
4:15-4:30 Break
4:40-5:10 Shmuel Muallem (UT Southwestern): Ca2+ entry in Ca2+ signaling and disease
5:10-5:40 Marshall Montrose (Univ Cincinnati):  Epithelial barrier and GI function
5:45-7:00 Dinner
7:15-8:00 Keynote SpeakerWilliam H. Bowen Lectureship
Larry Tabak (NIDCR): How Ira’s protein led me down a sugar coated trail
8:00-9:00 Reception

 

Saturday June 28

8:00-8:45 Breakfast
9:00-12:00 Session IV: Saliva – Biomarkers / Structure and Function
Co-Chairs: Daniel Malamud
& Stefan Ruhl
9:00-9:30 Daniel Malamud (NYU): Update on oral-based diagnostics for systemic diseases
9:30-10:00 Ignacio Sanz (Univ Rochester): B cells and the salivary glands.  Biomarker applications
10:00-10:30 Stefan Ruhl (SUNY-Buffalo): A proteomics-based search for bacterial recognition sites in human saliva
10:30-10:45 Break
10:55-11:25 Libuse Bobek (SUNY-Buffalo): Antimicrobial activity of MUC7 peptides
11:25-11:55 Michel Koo (Univ Rochester): Saliva-bacterial interactions - Influences on S. mutans
 biofilm formation
12:00 Boxed lunches available