 |
 |
Research Opportunities by Human Disease: Cancer | Cardiovascular
Disease | Endocrine
Disorders |
|
|
Cardiovascular disease remains the number one cause of death in our society despite a plethora of mechanical and pharmaceutical therapies. The epidemic of type II diabetes as well as the increasing age of baby-boomers will make a difficult situation even more challenging. The good news is that major advances in animal model discovery (e.g., mice, zebrafish), stem cell biology, and genetics provide a golden opportunity to translate basic findings in the laboratory to clinical studies for the treatment of cardiovascular disease. Faculty engaged in cardiovascular research are modeling heart failure, type II diabetes, congenital malformations of heart and/or blood vessels as well as vascular narrowing (e.g., hardening of the arteries). State-of-the-art techniques in genomics, genetics, and molecular biology are used to model disease and dissect basic signaling pathways that are activated by disease-inducing cues. Many faculty also are assessing novel methods of therapy in hopes of alleviating the morbidity and mortality linked to cardiovascular diseases. Faculty investigating cardiovascular disease: Bradford
Berk
|
Mouse models of arterial injury are used to understand the pathology of vascular disease and to develop novel therapeutic interventions (illustration couresy of Dr. Joseph Miano). |
